Breakthrough in stroke treatment: new drug restores without rehabilitation

Scientists from the University of California at Los Angeles (UCLA) have made a breakthrough in the treatment of the effects of stroke, having developed the first of its kind drug DDL-920, capable of restoring motor functions without the need for prolonged physical rehabilitation. This is evidenced by the data of the study, the results of which are published in Nature Communications, reports RTVI US.

The new drug has been successfully tested on mice. He has shown the ability to repair damaged neural connections, which opens up new perspectives for millions of patients suffering from the effects of stroke.

"Researchers have found that stroke disrupts communication between neurons located in areas of the brain far from the lesion. Stroke leads to the loss of so-called gamma oscillations — brain rhythms that coordinate the work of neural networks responsible for movement. During experiments on mice, scientists found that the drug DDL-920 restores these rhythms, thereby restoring lost connections and improving motor functions," the TV channel reports.

It is noted. that the drug DDL-920 was developed in the UCLA laboratory under the supervision of study co-author Dr. Varghese John. In experiments on mice, the drug has shown a significant improvement in movement control, however, the scientists emphasize, further studies are needed to assess its safety and effectiveness before starting clinical trials on humans.